NanoBio Interfaces

O conceito de Nano-Bio Interfaces faz referência não apenas à interface física entre nanoestruturas e sistemas biológicos, mas também à investigação dos efeitos dessa interação com um olhar integrado de áreas do conhecimento como Química, Física, Biologia, Farmácia e Ciências de Materiais. Tais esforços inter e multidisciplinares tornam possível a compreensão das propriedades biofísico-químicas e sua modulação a partir do design racional de novos nanomateriais aplicados às Ciências da Saúde.

Neste contexto, a proposta da criação do Grupo de Pesquisa em NanoBio Interfaces consolida uma nova área de pesquisa dentro da Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), voltada para a investigação, design e caracterização de nanomateriais com potencialidades na saúde, combinando expertises de diferentes campos experimentais, computacionais e teóricos.

Notícias e Avisos

Mai 30, 2026	Inscrições abertas — III Workshop do INCT_3D-Saúde: Desafios e Estratégias para Translação Clínica
Mai 09, 2025	II Workshop do INCT_3D-Saúde (14 a 16 de maio de 2025 - Centro Cultural da UFRGS)

Publicações Selecionadas

ACSomega

Semi-solid Extrusion 3D Printing of Chitosan/Carbon Nanotube Nanocomposite Films for Microextraction of Pesticides in Water

Giuseppe da Silva Salvador, Vítor Augusto Bauer, Rita de Cássia dos Reis Schmidt, and 9 more authors

ACS Omega, 2026

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ColSurfB

Polymeric nanocomposites in a biological interface: From a molecular view to final applications

RCR Schmidt, TE Oliveira, and Deon M.

Colloids and Surfaces B: Biointerfaces, 2025

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Polymeric nanocomposites have been valuable materials for the pharmaceutical and biomedical fields because they associate the unique properties of a material on a nanoscale with a polymeric matrix, with a synergistic outcome that improves their physical, chemical, and mechanical properties. Understanding the nature of the physical and chemical interactions and effects that take place at the polymer-nanomaterial interface is crucial to predict and explain how the nanocomposite behaves when set forth a health-related application and faces a biological interface. Therefore, this review aimed to assemble and examine experimental articles in which the molecular-level interaction between nanomaterials and polymer matrices were determinants of the biological outcome. For health applications, the nanocomposite systems were found to be most applied as antimicrobials, for tissue engineering, and for drug delivery. A plethora of biocompatible polymers have been reported, although for nanomaterials the most distinguished effects were attained with metal and metal oxide nanoparticles. The bioactivity of the nanocomposite was found to be dependent on features such as: colloidal size, release, and disintegration of the nanoparticle, controlled by the polymer matrix; hydrophilicity, degree of crosslinking, porosity, mechanical strength, and stability/responsiveness of the polymer, modified by the nanofiller; and the final charge and functional groups available at the whole nanocomposite surface. As a result, researchers can gather insights to design and characterize advanced polymeric nanocomposites with optimized performance for use in biomedical devices, drug delivery systems, and other therapeutic applications.